A SIMPLE KEY FOR TRACLEER UNVEILED

Ketoconazole Coadministration of bosentan 125 mg 2 times each day and ketoconazole, a potent CYP3A inhibitor, improved the plasma concentrations of bosentan by approximately one hundred% in ordinary volunteers. No dose adjustment of bosentan is essential, but amplified effects of bosentan should be viewed as.There are many possible confounders, eg,